The procedure of freezing eggs is quite sensitive and arduous successfully. The egg may be the largest cell in our body. It really is comprised mostly of drinking water and thus very hard to freeze without destroying it. Boston IVF uses technology that replaces the liquid with molecules that produce the egg less susceptible to freezing and even more viable for fertilization after they are thawed. Related StoriesNew Swedish research questions treatment of feminine infertility with stem cell therapyStudy: Visceral unwanted fat in early being pregnant can increase threat of gestational diabetesNew research discovers high prevalence of HIV among pregnant refugee ladies in Ontario’The pregnancy caused by this research is a significant milestone for Boston IVF and keeps enormous promise for sufferers who hope to protect their fertility by freezing their eggs in order to become pregnant at another time within their lives,’ stated.‘We were thinking about trying to understand why specific MHC molecules are linked to autoimmune disease, particularly type 1 diabetes,’ said Study Associate Adam Corper of the Wilson laboratory, who was first author of the paper with Kenji Yoshida of the Teyton laboratory.’ Breaking Tolerance In the new research, the group used a number of structural and biophysical research to answer that question. Previously, Teyton and Wilson labs acquired determined the structure of a ‘diabetogenic’ MHC molecule and found that mutations to position 57 caused only delicate changes. It didn’t, as some experienced speculated, cause the molecule to be unstable and non-functional. Now, in the new study the researchers discovered that diabetes-causing mutations transformed the charge at one end of the MHC peptide-binding groove.